I've been using a 4GB on an rPI "clone" - the Banana PI - and have been happy so far with everything the board has to offer, as a headless server. However, I started getting some errors after ~3 years of usage, with the card and at one point it stopped booting completely. Nice timing as well, it's not fun losing your music streaming server at Christmas time.
Long story short, the card has been used at 80-90% most of the time, which left very little space for wear leveling. I hooked it up to HDMI and could see a lot of error messages on the screen about mmc. So the card was dead and I feared the worst. last backup having been made a month prior to this.
Never fear, just writing imaging the card (Win32DiskImager) and copying the image to another 16GB card worked fine. So if you run into this it might be worth it to just try and duplicate the card to another one. In my case, no other changes were required.